Prínos natriuretických peptidov pre diagnózu, prognózu, manažment a liečbu srdcového zlyhávania

Interní Med. 2006; 8(10): 428-431

Merit of natriuretic peptides for diagnosis, prognosis, management and therapy of heart failure

Eva Goncalvesová: Transplantačné oddelenie, Slovenský ústav srdcových a cievnych chorôb, Bratislava

Natriuretic peptides are a group of hormones with important regulatory roles in the cardiovascular system. During the past five years, determination of level of BNP or a part of its precursor, so-called N-terminal pro-BNP, has become widely spread in the diagnostics and management of heart failure. Recombinant BNP – nesiritide – has been increasingly used for treatment of acute decompensation of heart failure in the U. S. The paper deals with issues of physiology of natriuretic peptides and use of measurement of serum level of BNP in clinical practice, as well as experience with therapeutic use of BNP.