Interní Med. 2008; 10(12): 569-574 [Prakt. lékáren. 2008; 4(4): 166-171]

Pharmacology of insomnia

MUDr. Miroslav Moráň
Centrum pro diagnostiku a léčbu poruch spánku a bdění

The paper briefly deals with the basic features of insomnia, its possible causes and therapeutic options; a more detailed overview is given of the pharmacology of insomnia including its classification based on types of insomnia.

Keywords: Key words: insomnia, hypnotics, antidepressants, intermittent treatment.

Published: January 1, 2009  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Moráň M. Pharmacology of insomnia. Interní Med. 2008;10(12):569-574.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. American Academy of Sleep Medicine: The Classification of Sleep Disorders. Diagnostic and Coding Manual, 2nd Edition. 2005, Illinois, AASM.
    2. Arbus L, Lavoisy J, Soubrane C, Belin J. Efficacy and safety of zolpidem 10 mg administered pro renata (P.R.N.) in patients with chronic insomnia: a multicenter, placebo controlled study. Sleep Res Online 1999; 2(Suppl) 1): 129. Go to original source...
    3. Benca RM. Diagnosis and treatment of chronic insomnia: a review. Psychiatr Serv. 2005; 56: 332-343. Go to original source... Go to PubMed...
    4. Bixler EO, Kales A, Soldatos CR, et al. Prevalence of sleep disorders in the Los Angeles metropolitan area. Am J Psychiatry 1979; 136: 1257-1262. Go to original source... Go to PubMed...
    5. Cluydts R, Peeters K, de Bouyalsky I, Lavoisy J. Comparison of continuous versus intermitent administration of zolpidem in chronic insomniasc: a double blind, randomized pilot study. J. Int. Med. Res 1998; 26: 13-24. Go to original source... Go to PubMed...
    6. Jirák R. Farmakoterapie poruch spánku ve stáří a u pacientů s organickým psychosyndromem. Praha: Remedia 1994; 4: 238-240.
    7. Kales A, Kales JD. Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects. J Clin Psychopharmacol 1983; 3: 140-150. Go to original source... Go to PubMed...
    8. Kales A, Scharf M, Kales J. Rebound insomnia: a new clinical syndrome. Science 1978; 201: 1039-1041. Go to original source... Go to PubMed...
    9. Nevšímalová S, Šonka K. Poruchy spánku a bdění. Praha: Galén; 2007; 1-345. 1995; 18(9): 787-796.
    10. Nierenberg AA, Adler LA, Paselow E, Zornberg G, Rosenthal M. Trazodone for antidepressant-associated insomnia. Am J Psychiatry 1994; 151: 1069-1072. Go to original source... Go to PubMed...
    11. Nierenberg AA, Keck PE Jr. Management of monoamine oxidase inhibitor-associated insomnia with trazodone. J Clin Psychopharmacol 1989; 8: 42-45. Go to original source...
    12. Nofzinger EA, Reynolds CF III, Thase ME, Frank E, Jennings JR, Fasiczka AL, et al. REM sleep enhancement by bupropion in depressed men. Am J Psychiatry 1995; 152: 274-276. Go to original source... Go to PubMed...
    13. Ott GE, Rao U, Nuccio I, Lin KM, Poland RE. Effect of bupropion-SR on REM sleep: relationship to antidepressant response. Psychopharmacology (Berl) 2002; 165: 29-36. Go to original source... Go to PubMed...
    14. Reynolds CF III, Buyse DJ, Brunner DP, Begley AE, Dew MA, Hoch CC, et al. Maintenance nortriptyline effects on electroencephalographic sleep in elderly patients with recurrent major depression: double-blind, placebo - and plasma-level-controlled evaluation. Biol Psychiatry 1997; 42: 560-567. Go to original source... Go to PubMed...
    15. Rickels K. Clinical trials and hypnotics. J Clin Psychopharmacol 1983; 3: 133. Go to original source... Go to PubMed...
    16. Roth T, Zorick F, Witting R, McLenaghan A, Roehrs T. The effects of doxepin HCl on sleep and depression. J Clin Psychiatry 1982; 43: 366-368.
    17. Schittecatte M, Dumont F, Machowski R, Cornil C, Lavergne F, Wilmotte J. Effects of mirtazapine on sleep polygraphic variables in major depression. Neuropsychobiology 2002; 46: 197-201. Go to original source... Go to PubMed...
    18. Šonka K, et al. Apnoe a další poruchy dýchání ve spánku. Praha: Galén; 2004.
    19. Šonka K. Syndrom neklidných nohou. Praha: Jesenius-Maxdorf; 2006.
    20. Švestka J, et al. Psychofarmaka v klinické praxi. Praha: Grada, 1995.
    21. Thase ME. Treatment issues related to sleep and depression. J Clin Psychiatry 2000; 61(Suppl 11): 46-50.
    22. Wincor MZ. Insomnia and the new benzodiazepines. Clin Pharm 1982; 1: 425-432. Go to PubMed...

    Return to the content


    Internal Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.