Interní Med. 2009; 11(7): 324-326
Prevention of contrast-induced nephropathy in patients with chronic renal insufficiency
- Klinika nefrologie 1. LF UK a VFN, Praha
Renal toxicity of iodinated radiocontrast media is a major cause of acute renal failure in hospitalised patients. The incidence of contrast-
induced nephropathy in patients with chronic renal insufficiency is about 30 %. The most optimal preventive strategy is adequate
hydration, rational indication of invasive procedures and the use of iso-osmolar, non-ionic contrast-media. N-acetylcystein is often
discussed as a preventive drug in recent years. It was found recently, that gadolinium-enhanced magnetic resonance can lead to acute
renal failure in patients with chronic renal insufficiency. Moreover, gadolinium is associated with a severe, life-threatening nephrogenic
systemic fibrosis in patients with renal insufficiency.
Keywords: contrast media, nephropathy, hydratation, acetylcystein, bicarbonate.
Published: September 1, 2009 Show citation
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