Interní Med. 2010; 12(1): 41-43
How to proceed when the acute phase of myocardial infarction is not treated in time
- Kardiologická klinika, Krajská zdravotní a.s., Masarykova nemocnice Ústí nad Labem
- V interní a kardiologické praxi se setkáváme s infarktem myokardu v subakutní fázi nebo po nedávno prodělaném infarktu myokardu
Subacute phase myocardial infarction as well as angina pectoris or manifestations of heart failure following a recent myocardial infarction
are encountered in internal medicine and cardiological practice. It is not uncommon that coronary revascularization is no longer
technically feasible. The case report describes the management of invasive diagnostic procedures and subsequent pharmacotherapy
of myocardial infarction. The pharmacotherapy of the patient combines prognostic drugs as well as drugs improving the quality of life
by affecting the symptoms, but also drugs affecting the metabolism of ischaemic myocardium.
Keywords: angina pectoris, acute myocardial infarction, percutaneous coronary intervention, trimetazidine
Published: May 1, 2010 Show citation
References
- Bělohlávek J, Aschermann M. Doporučený postup pro diagnostiku a léčbu akutních koronárních syndromů bez elevací ST úseků na EKG. Cor Vasa 2008; 50 (Suppl): 1S7-1S23.
- Fragasso G, Palloshi A, Puccetti P, et al. A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure. J Am Coll Cardiol 2006; 48: 992-998.
Go to original source... 
Go to PubMed... - Hradec J. Kombinační léčba anginy pectoris. Remedia 2006; 16: 237-242.
- Krupička J. Komentář ke studii. Význam trimetazidinu u srdečního selhání. Farmakoterapie 2007; 6: 590.
- Bonello, et al. Trimetazidine and reduction in mortality and hospitalization in patients with ischemic dilated cardiomyopathy: a post hoc analysis of the Villa Pini d'Abruzzo trimetazidine trial. Protective effect of an acute oral loading dose of trimetazidine on myocardial injury. Heart 2007; 93: 703-707. Go to original source... Go to PubMed...
- Belardinelli R, Lacalaprice F, Faccenda E, et al. Trimetazidine potentiates the effects of exercise training in patients with ischemic cardiomyopathy referred for cardiac rehabilitation. Eur J Cardiovasc Prev Rehabil 2008; 15: 533-540. Go to original source... Go to PubMed...
- Chazov EL, Lepakchin VK, Zharova VA, et al. Trimetazidine in Angina Combination Therapy - The TACT Study: trimetazidine versus conventional treatment in patients with stable angina pectoris in a randomized, placebo-controlled, multicenter study. Am J Ther 2005; 12; 35-42. Go to original source... Go to PubMed...
- Napoli PD, Giovanni PD, Gaeta MA, et al. Trimetazidine and reduction in mortality and hospitalization in patients with ischemic dilated cardiomyopathy. J Cardiovasc Pharmacol. 2007; 50(5): 585-589. Go to original source... Go to PubMed...