Interní Med. 2010; 12(12): 585-589

The specifics of non-invasive testing in women with suspected ischemic heart disease

MUDr.Aleš Tomášek1, doc.MUDr.Stanislav Janoušek, CSc.2, doc.MUDr.Petr Němec, CSc.1
1 Centrum kardiovaskulární a transplantační chirurgie Brno
2 Interní kardiologická klinika FN Brno

Coronary artery disease (CAD) is the leading cause of cardiovascular mortality in developed countries. The occurence of CAD is delayed in

women. The women´s CAD symptoms are often atypical or they are completely lacking. The noninvasive examination methods including

some imaging procedures have a specific pitfalls in women. Therefore the identification of CAD in females is more difficult and there is

a higher risk of misdiagnostic in them with potential fatality, especially in acute coronary syndromes.

Keywords: CAD, women, noninvasive diagnostic methods

Published: December 15, 2010  Show citation

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Tomášek A, Janoušek S, Němec P. The specifics of non-invasive testing in women with suspected ischemic heart disease. Interní Med. 2010;12(12):585-589.
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    References

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    88. Khanal S, Daggubati RB, Pai RG. Effect of gender and left ventricular dysfunction on the incidence of hypotension induced by dobutamine stress echocardiography. J Am Soc Echocardiogr. 1998; 11: 1134-1138. Go to original source... Go to PubMed...
    89. Taillefer R, DePuey EG, Udelson JE, et al. Comparative diagnostic accuracy of Tl-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECG-gated SPECT) in detecting coronary artery disease in women. J Am Coll Cardiol. 1997; 29: 69-77. Go to original source... Go to PubMed...
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    91. Hansen CL, Crabbe D, Rubin S. Lower diagnostic accuracy of thallium-201 SPECT myocardial perfusion imaging in women: an effect of smaller chamber size. J Am Coll Cardiol. 1996; 28: 1214-1219. Go to original source... Go to PubMed...
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    95. Higginbotham MB, Morris KG, Coleman RE, et al. Sex-related differences in the normal cardiac response to upright exercise. Circulation 1984; 70: 357-366. Go to original source... Go to PubMed...
    96. Bellasi A, Lacey C, Taylor AJ, et al. Comparison of prognostic usefulness of coronary artery calcium in men versus women (results from a meta- and pooled analysis estimating allcause mortality and coronary heart disease death or myocardial infarction). Am J Cardiol. 2007; 100(3): 409-414. Go to original source... Go to PubMed...
    97. Haberl R, Becker A, Leber A, et al. Correlation of coronary calcification and angiographically documented stenoses in patients with suspected coronary artery disease: results of 1 764 patients. J Am Coll Cardiol 2001; 37: 451-457. Go to original source... Go to PubMed...
    98. Rubinshtein R, Gaspar T, Halon DA, et al. Prevalence and extent of obstructive coronary artery disease in patients with zero or low calcium score undergoing 64-slice cardiac multidetector computed tomography for evaluation of a chest pain syndrome. Am J Cardiol 2007; 99: 472-475. Go to original source... Go to PubMed...
    99. Howard G, Sharrett AR, Heiss G, et al. Carotid artery intimal-medial thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators. Stroke 1993; 24: 1297-1304. Go to original source... Go to PubMed...
    100. Kablak-Ziembicka A, Przewlocki T, Tracz W, et al. Gender differences in carotid intima-media thickness in patients with suspected coronary artery disease. Am J Cardiol 2005; 96: 1217-1222. Go to original source... Go to PubMed...
    101. Pundziute G, Schuijf JD, Jukema JW, et al. Gender influence on the diagnostic accuracy of 64-slice multislice computed tomography coronary angiography for detection of obstructive coronary artery disease. Heart 2008; 94: 48-52. Go to original source... Go to PubMed...
    102. Shaw LJ, Min JK, Narula JM, et al. Sex Differences in Mortality Associated With Computed Tomographic Angiographic Measurements of Obstructive and Nonobstructive Coronary Artery Disease. Circ Cardiovasc Imaging 2010; 3: 473-481. Go to original source... Go to PubMed...
    103. Leschka S, Alkadhi H, Plass A, et al. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J 2005; 26: 1482-1487. Go to original source... Go to PubMed...
    104. Halon DA, Gaspar T, Adawi S, et al. Uses and limitations of 40 slice multi-detector row spiral computed tomography for diagnosing coronary lesions in unselected patients referred for routine invasive coronary angiography. Cardiology 2007; 108: 200-209. Go to original source... Go to PubMed...
    105. Wilke NM, Jerosch-Herold M, Zenovich A, Stillman AE. Magnetic resonance first-pass myocardial perfusion imaging: clinical validation and future applications. J Magn Reson Imaging 1999; 10: 676-685. Go to original source... Go to PubMed...
    106. Nagel E, Lehmkuhl HB, Bocksch W, et al. Noninvasive diagnosis of ischemia-induced wall motion abnormalities with the use of high-dose dobutamine stress MRI: comparison with dobutamine stress echocardiography. Circulation 1999; 99: 763-770. Go to original source... Go to PubMed...

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