Interní Med. 2019; 21(5): 280-283

News in the treatment of hemophilia

MUDr. Antonín Hluší, Ph.D.
Hemato‑onkologická
klinika FNOL a LF UP v Olomouci

The prognosis and quality of life of haemophilia patients has changed dramatically with the use of coagulation factor concentrates.
In the last two decades, the quality of care has improved considerably thanks to the availability of costly treatment, the
use of prophylactic therapy, the use of safe intravenous recombinant products and comprehensive care in haemophilia centres.
Recent trends include therapy with extended half-life, individualization of pharmacokinetics or a completely innovative approach
using non-factor therapy with the subcutaneously administered bispecific antibody emicizumab replacing factor VIII function.

Keywords: hemophilia, pharmakocinetics, EHL, emicizumab

Published: December 1, 2019  Show citation

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Hluší A. News in the treatment of hemophilia. Interní Med. 2019;21(5):280-283.
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